Leukotriene C4-d5

Leukotriene C4-d5
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10006198-25 25 µg -

5 - 10 Werktage*

287,00 €
Cay10006198-50 50 µg -

5 - 10 Werktage*

544,00 €
Cay10006198-100 100 µg -

5 - 10 Werktage*

1.030,00 €
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20... mehr
Produktinformationen "Leukotriene C4-d5"
Leukotriene C4-d5 (LTC4-d5) contains five deuterium atoms at the 19, 19', 20, 20 and 20 positions. It is intended for use as an internal standard for the quantification of LTC4 by GC- or LC-mass spectrometry. LTC4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. The concentration of LTC4 required to produce marked contractions of lung parenchymal strips and isolated tracheal rings is about 1 nM. Formal Name: 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid. CAS Number: 1441421-73-3. Synonyms: LTC4-d5. Molecular Formula: C30H42D5N3O9S. Formula Weight: 630.8. Purity: >99% deuterated forms (d1-d5). Formulation: A solution in ethanol:water (95:5). Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 1 mg/ml, Ethanol:H20 (95:5): 2 mg/ml, PBS (pH 7.2): 0.1 mg/ml. lambdamax: 280 nm. SMILES: O[C@@H](CCCC(O)=O)[C@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)/C=C/C=C/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,. InChi Key: GWNVDXQDILPJIG-PTOIOBJSSA-N.
Schlagworte: LTC4-d5, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-d5-eicosatetraenoic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 10006198


Anwendung: Standard
MW: 630.8 D
Formel: C30H42D5N3O9S
Reinheit: >99% deuterated forms (d1-d5)
Format: Solution

Datenbank Information

CAS : 1441421-73-3| Finde Alternativen
KEGG ID : K00807 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -80°C)
Signalwort: Danger
H-Sätze: H225
P-Sätze: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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