Econazole (nitrate)

Econazole (nitrate) is an azole-based antifungal compound that acts by inhibiting the 14alpha-demethylation of lanosterol (Cay-19521), which consequently leads to the inhibition of ergosterol (Cay-19850) synthesis in fungal cell membranes. It demonstrates broad-spectrum activity against dermatophytes, Candida species, other pathogenic yeasts, and some Gram-positive bacteria.Formal Name: 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, mononitrate. CAS Number: 24169-02-6. Synonyms: NSC 243115, SQ 13,020. Molecular Formula: C18H15Cl3N2O . HNO3. Formula Weight: 444.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/mL, DMSO: 25 mg/mL, DMSO:PBS(pH 7.2) (1:2): 0.3 mg/mL, Ethanol: 0.1 mg/mL. SMILES: ClC1=CC(Cl)=CC=C1C(CN2C=NC=C2)OCC3=CC=C(Cl)C=C3.O=[N](O)=O. InChi Code: InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21,2-1(3)4/h1-9,12,18H,10-11H2,(H,2,3,4). InChi Key: DDXORDQKGIZAME-UHFFFAOYSA-N.