Y-27632

Description: Y-27632 is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. Target: Apoptosis, ROCK. Smiles: C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1. References: Wu Y, et al. ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset induced pluripotent stem cells by suppressing expression and activity of caspase 3. Theriogenology. 2016 Jan 15,85(2):302-14.