WT-161

Description: WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM). Target: Apoptosis, HDAC. Smiles: N(C1=CC=C(C=NNC(CCCCCCC(NO)=O)=O)C=C1)(C2=CC=CC=C2)C3=CC=CC=C3. References: Hideshima T , Qi J , Paranal R M , et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma[J]. Proceedings of the National Academy of Sciences, 2016:201608067.