WAY-316606

An inhibitor of sFRP1 (IC50 = 0.5 µM), increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 µM), increases total bone area in a murine calvarial organ culture assay at 0.1 nM. SMILES: O=S(C1=CC=CC=C1)(C2=CC=C(C(F)(F)F)C(S(NC3CCNCC3)(=O)=O)=C2)=O. InChi Code: InChI=1S/C18H19F3N2O4S2/c19-18(20,21)16-7-6-15(28(24,25)14-4-2-1-3-5-14)12-17(16)29(26,27)23-13-8-10-22-11-9-13/h1-7,12-13,22-23H,8-11H2. InChi Key: ITBGJNVZJBVPLJ-UHFFFAOYSA-N