Zu "K02166" wurden 40 Artikel gefunden!
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WAY-316606
Artikelnummer: Cay45425-1
An inhibitor of sFRP1 (IC50 = 0.5 µM), increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 µM), increases total bone area in a murine calvarial organ culture assay at 0.1 nM. SMILES: O=S(C1=CC=CC=C1)(C2=CC=C(C(F)(F)F)C(S(NC3CCNCC3)(=O)=O)=C2)=O. InChi Code:...
| Schlagworte: | 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluor omethyl)-benzenesulfonamide |
| Anwendung: | sFRP1 inhibitor |
| CAS | 915759-45-4 |
| MW: | 448.48 D |
ab 134,00 €
SFRP1/SARP2, His, Human
Artikelnummer: GSC-Z05812-100
Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to the loss of expression in various human cancers, which is mainly attributed by epigenetic inactivation via DNA methylation or transcriptional...
| Schlagworte: | SFRP1, Secreted frizzled-related protein 1, Secreted apoptosis-related protein 2 |
| Ursprungsart: | human |
| MW: | 33.63 kD |
ab 632,00 €
Human SFRP1 / Secreted frizzled-related protein 1 ELISA Kit
Artikelnummer: G-HUFI01068.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-SFRP1 (Secreted Frizzled Related Protein-1, SARP2,...
Artikelnummer: 600-401-475
Protein function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular...
| Schlagworte: | Anti-FRP, Anti-SFRP1, Anti-FRP-1, Anti-sFRP-1, Anti-SARP-2, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
Anti-SFRP1
Artikelnummer: 600-401-475S
This affinity purified antibody is directed against human SFRP protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human based on 100% homology for the immunogen sequence. Expect cross reactivity...
| Schlagworte: | Anti-FRP, Anti-SFRP1, Anti-FRP-1, Anti-SARP-2, Anti-sFRP-1, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
180,00 €
Anti-SFRP1
Artikelnummer: NSJ-R34542-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Secreted frizzled-related protein 1 Protein function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in...
| Schlagworte: | Anti-FRP, Anti-FRP-1, Anti-SFRP1, Anti-sFRP-1, Anti-SARP-2, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-SFRP1
Artikelnummer: E-AB-16059.120
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is...
| Schlagworte: | Anti-FRP, Anti-FRP-1, Anti-SFRP1, Anti-sFRP-1, Anti-SARP-2, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
WAY-316606
Artikelnummer: Cay26324-1
WAY-316606 is an inhibitor of secreted frizzled-related protein 1 (sFRP1, IC50 = 0.5 µM). It increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 µM). WAY-316606 increases total bone area in a murine calvarial organ culture assay when used at concentrations greater than 0.1 nM.Formal Name:...
| Schlagworte: | 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-benzenesulfonamide |
| Anwendung: | sFRP-1 inhibitor |
| CAS | 915759-45-4 |
| MW: | 448.5 D |
ab 56,00 €
Anti-SFRP1
Artikelnummer: NSJ-RQ4938
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Secreted frizzled-related protein 1, also known as SFRP1, is a protein which in humans is encoded by the SFRP1 gene. It is mapped to 8p11.21. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative...
| Schlagworte: | Anti-FRP, Anti-SFRP1, Anti-FRP-1, Anti-SARP-2, Anti-sFRP-1, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | WB, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-SFRP1
Artikelnummer: ARG41773.50
Protein function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular...
| Schlagworte: | Anti-FRP, Anti-SFRP1, Anti-FRP-1, Anti-SARP-2, Anti-sFRP-1, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
551,00 €
Anti-SFRP1
Artikelnummer: ARG41820.100
Protein function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular...
| Schlagworte: | Anti-FRP, Anti-SFRP1, Anti-FRP-1, Anti-SARP-2, Anti-sFRP-1, Anti-Secreted frizzled-related protein 1, Anti-Secreted... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
sFRP1 (human, recombinant)
Artikelnummer: Cay38061-50
Secreted frizzled-related protein 1 (sFRP1) is a Wnt inhibitor and a member of the sFRP family. It is composed of a signal peptide, a cysteine-rich domain, and a netrin-like domain. sFRP1 is ubiquitously expressed, with the highest levels in the heart, ovary, testis, and small intestine. It inhibits Wnt signaling by...
| Schlagworte: | FRP, SFRP1, FRP-1, FRP-1, sFRP-1, SARP-2, sFRP-1, SARP-2, Secreted frizzled-related protein 1, Secreted frizzled-related... |
| Anwendung: | Active |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 34 kD |
368,00 €