VPS34-IN-19

Artikelnummer	Größe	Manual	SDB	Lieferzeit	Preis
Cay41357-5	5 mg	-	-	6 - 10 Werktage*	142,00 €
Cay41357-10	10 mg	-	-	6 - 10 Werktage*	270,00 €
Cay41357-50	50 mg	-	-	6 - 10 Werktage*	987,00 €
Cay41357-100	100 mg	-	-	6 - 10 Werktage*	1.408,00 €

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An inhibitor of VPS34 (IC50 = 15 nM), selective for VPS34 over PI3Kdelta (IC50 = 802 nM) and... mehr

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Produktinformationen "VPS34-IN-19"

An inhibitor of VPS34 (IC50 = 15 nM), selective for VPS34 over PI3Kdelta (IC50 = 802 nM) and PI3Kalpha, PI3Kbeta, and PI3Kgamma (IC50s = >802 nM for all), increases intratumoral levels of LC3-II, a marker of autophagy but does not reduce tumor volume in an RKO colon cancer mouse xenograft model at 50 mg/kg twice per day, reduces SARS-CoV-2 viral titers in isolated human lung tissue at 2.5 and 5 µM. Formulation: A solid. InChI: InChI=1S/C21H25N7O/c1-21(2,29)13-25-19-24-12-16(18(28-19)11-14-3-4-14)17-7-10-23-20(27-17)26-15-5-8-22-9-6-15/h5-10,12,14,29H,3-4,11,13H2,1-2H3,(H,24,25,28)(H,22,23,26,27). InChIKey: XJTIGGCBXFIZJV-UHFFFAOYSA-N. SMILES: CC(C)(O)CNC1=NC(CC2CC2)=C(C=N1)C3=NC(NC4=CC=NC=C4)=NC=C3

Schlagworte:	Compound 19, Vacuolar Protein Sorting 34 Inhibitor 19, VPS Inhibitor 19, 1-[[4'-(cyclopropylmethyl)-2-(4-pyridinylamino)[4,5'-bipyrimidin]-2'-yl]amino]-2-methyl-2-propanol
Hersteller:	Cayman Chemical
Hersteller-Nr:	41357

Eigenschaften

Anwendung:	VPS34 inhibitor
Immunogen:	391.5
MW:	391.5 D
Formel:	C21H25N7O
Reinheit:	>98%
Format:	Solid

Datenbank Information

CAS :	1383716-46-8\| Passende Produkte
KEGG ID :	K00914 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H302, H315, H319, H335
P-Sätze:	P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501