Zu "K00914" wurden 77 Artikel gefunden!
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Mouse PIK3C3 (Phosphoinositide-3-Kinase Class 3) ELISA Kit
Artikelnummer: ELK-ELK7518.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PIK3C3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PIK3C3....
| Schlagworte: | PI3K type 3, PI3-kinase type 3, PtdIns-3-kinase type 3, Phosphoinositide-3-kinase class 3, Phosphatidylinositol 3-kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat PIK3C3 (Phosphoinositide-3-Kinase Class 3) ELISA Kit
Artikelnummer: ELK-ELK0649.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PIK3C3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PIK3C3. Next,...
| Schlagworte: | Vps34, PI3K type 3, PI3-kinase type 3, PtdIns-3-kinase type 3, Phosphoinositide-3-kinase class 3, Phosphatidylinositol... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human PIK3C3 (Phosphoinositide-3-Kinase Class 3) ELISA Kit
Artikelnummer: ELK-ELK5138.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PIK3C3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PIK3C3....
| Schlagworte: | hVps34, PI3K type 3, PI3-kinase type 3, PtdIns-3-kinase type 3, Phosphoinositide-3-kinase class 3, Phosphatidylinositol... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Vps34-IN1
Artikelnummer: Cay17392-1
Vps34-IN1 is a potent inhibitor of the class III phosphoinositide 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34, IC50 = 25 nM in vitro). It does not significantly inhibit the activity of over 340 additional kinases, including class I and II PI3Ks. Vps34-IN1 dose-dependently inhibits generation of PtdIns-(3)-p,...
| Schlagworte: | Vacuolar Protein Sorting 34 Inhibitor 1, Vps34 Inhibitor 1,... |
| Anwendung: | Phosphatidylinositol 3-kinase inhibitor |
| CAS | 1383716-33-3 |
| MW: | 425.9 D |
ab 34,00 €
SAR405
Artikelnummer: Cay16979-1
SAR405 is an inhibitor of the phosphoinositide 3-kinase (PI3K) class III isoform Vps34 (IC50 = 1.2 nM). It is without effect (IC50 > 10,000 nM) on other PI3K isoforms and mTOR. SAR405 alters vesicle trafficking and inhibits autophagy by blocking autophagosome formation. SAR405 also synergizes with the mTOR inhibitor...
| Schlagworte: | (8S)-9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1... |
| Anwendung: | PIK3C3 / Vps34 inhibitor |
| CAS | 1523406-39-4 |
| MW: | 443.9 D |
ab 62,00 €
PIK-III
Artikelnummer: Cay17002-1
PIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) that binds a unique hydrophobic pocket (IC50 = 18 nM). It is selective for Vps34 over related PI3K isoforms, PI4Kbeta, and mTOR. PIK-III acutely inhibits autophagy and de novo lipidation of LC3, leading to...
| Schlagworte: | Vacuolar Protein Sorting 34 Inhibitor 2, Vps34 Inhibitor 2, Vps34-IN2,... |
| Anwendung: | VPS34 inhibitor |
| CAS | 1383716-40-2 |
| MW: | 319.4 D |
ab 100,00 €
Anti-PIK3C3
Artikelnummer: 600-401-DN6
Anti-PIK3C3 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PIK3C3 antibody is human, mouse and rat reactive. Protein function: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and...
| Schlagworte: | Anti-VPS34, Anti-hVps34, Anti-PIK3C3, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
684,00 €
Anti-PIK3C3
Artikelnummer: E-AB-16184.120
Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme that in humans is encoded by thePIK3C3 gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to...
| Schlagworte: | Anti-hVps34, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
NVP-BAG956
Artikelnummer: Cay24195-1
NVP-BAG956 is a dual inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50 = 245 nM) and class I phosphatidylinositol 3-kinase catalytic subunits (PI3Ks, IC50s = 56, 446, 35, and 117 nM for p110alpha, p110beta, p110delta, and p110gamma, respectively). It inhibits phosphorylation of T308-PKB (IC50 =...
| Schlagworte: | BAG956, alpha,alpha-dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Anwendung: | PDK1 inhibitor, PI3K inhibitor |
| CAS | 853910-02-8 |
| MW: | 427.5 D |
ab 50,00 €
Autophinib
Artikelnummer: Cay27320-1
Autophinib is an ATP-competitive inhibitor of the PI3K VPS34 (IC50 = 19 nM). It inhibits autophagy induced by the mTOR inhibitor rapamycin (Cay-13346) or by amino acid starvation (IC50s = 40 and 90 nM, respectively) in MCF-7 cells. Autophinib also induces apoptosis in amino acid-starved MCF-7 cells with an EC50...
| Schlagworte: | 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-4-pyrimidinamine |
| Anwendung: | VPS34 inhibitor |
| CAS | 1644443-47-9 |
| MW: | 346.7 D |
ab 43,00 €
Anti-PI3 Kinase Class III
Artikelnummer: ARG54876.100
Protein function: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and...
| Schlagworte: | Anti-hVps34, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-PIK3C3
Artikelnummer: E-AB-67600.120
Phosphatidylinositol 3-kinase catalytic subunit type 3is anenzymethat in humans is encoded by thePIK3C3gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to...
| Schlagworte: | Anti-hVps34, Anti-PI3K type 3, EC=2.7.1.137, Anti-PI3-kinase type 3, Anti-PtdIns-3-kinase type 3,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 317,00 €