Ubiquinol

Ubiquinol is a reduced form of coenzyme Q10 (CoQ10, Cay-11506), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.Formal Name: 2-[3,7,11,15,19,23,27,31,35,39-decamethyl-2E,6E,10E,14E,18E,22E,26E,30E,34E,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzenediol. CAS Number: 992-78-9. Synonyms: Dihydro Coenzyme Q10, Reduced Coenzyme Q10. Molecular Formula: C59H92O4. Formula Weight: 865.4. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: soluble. SMILES: COC1=C(OC)C(O)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)\C)C(C)=C1O. InChi Code: InChI=1S/C59H92O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42,60-61H,15-23,25,2. InChi Key: QNTNKSLOFHEFPK-FPXYFCFXSA-N.