TrkA Inhibitor

A TrkA inhibitor (IC50 = 0.063 µM), selective for TrkA over Cdk2 and C-RAF in a cell-free assay (IC50s = >10 µM for both), inhibits T. brucei GSK3 in a cell-free assay (IC50 = 2.81 µM). SMILES: NS(=O)(C1=CC=C(NC=C(C2=C(N3)C=CC=C2)C3=O)C=C1)=O. InChi Code: InChI=1S/C15H13N3O3S/c16-22(20,21)11-7-5-10(6-8-11)17-9-13-12-3-1-2-4-14(12)18-15(13)19/h1-9,17H,(H,18,19)(H2,16,20,21). InChi Key: PWGAHYYSCYXLLY-UHFFFAOYSA-N