Totrombopag choline

Description: Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies. Target: Others. Smiles: C[N+](C)(C)CCO.CC1=NN(C(=O)C1N=Nc1cccc(-c2cccc(c2)-c2nnn[n-]2)c1O)c1ccc(C)c(C)c1