Zu "K05082" wurden 44 Artikel gefunden!
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Mouse MPL / TPOR ELISA Kit
Artikelnummer: ARG82349.96
Protein function: Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [The UniProt Consortium]
| Schlagworte: | Mpl, Tpor, TPO-R, CD110, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.151,00 €
c-MPL/Thrombopoietin R, His, Mouse
Artikelnummer: GSC-Z06068-100
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of...
| Schlagworte: | Mpl, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein |
| Ursprungsart: | mouse |
| MW: | 52.3 kD |
ab 551,00 €
Lusutrombopag
Artikelnummer: Cay26533-1
Lusutrombopag is an agonist of the thrombopoietin receptor. It induces proliferation of Ba/F3 cells expressing human MPL, the gene for the thrombopoietin receptor, with an EC50 value of 84 nM but not of those expressing mouse Mpl. Lusutrombopag (0.3-10 mg/kg per day) increases the number of circulating platelets in...
| Schlagworte: | (2E)-3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-2-pro... |
| Anwendung: | Thrombopoietin receptor agonist |
| CAS | 1110766-97-6 |
| MW: | 591.5 D |
ab 58,00 €
Eltrombopag Olamine
Artikelnummer: TGM-T6825-10mg
Description: Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active small-molecule, nonpeptide thrombopoietin receptor agonist that stimulates megakaryopoiesis. It binds to and activates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), promoting the proliferation...
| Schlagworte: | Eltrombopag diethanolamine salt, Revolade, SB-497115GR, SB497115, Promacta Olamine |
| Anwendung: | Targets thrombopoietin receptor (TPOR, MPL, CD110) |
| CAS | 496775-62-3 |
| MW: | 564.63 D |
ab 35,00 €
Eltrombopag-13C4
Artikelnummer: Cay26114-1
Eltrombopag-13C4 is intended for use as an internal standard for the quantification of eltrombopag (Cay-13247) by GC- or LC-MS. Eltrombopag is an orally bioavailable nonpeptide agonist of the thrombopoietin receptor (EC50 = 0.27 µM in a reporter assay) and an iron chelator. It increases STAT5 phosphorylation in...
| Schlagworte: | (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-(methyl-13C)-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene-3,4,5-13C3)hydrazineyl)-2'-hydroxy... |
| Anwendung: | GC-MS, LC-MS, internal standard, TpoR agonist |
| MW: | 446.4 D |
ab 344,00 €
Avatrombopag
Artikelnummer: Cay26535-10
Avatrombopag is an agonist of the thrombopoietin receptor. It induces proliferation of Ba/F3 cells expressing the thrombopoietin receptor (EC50 = 3.3 nM) and induces differentiation of hematopoietic progenitor cells into megakaryotes. Avatrombopag is species-specific, inducing STAT5 phosphorylation in human and...
| Schlagworte: | AKR 501, AS 1670542, YM477,... |
| Anwendung: | Thrombopoietin receptor agonist |
| CAS | 570406-98-3 |
| MW: | 649.7 D |
ab 139,00 €
![TPOR Reporter Assay System [Human]](https://www.biomol.com/media/image/04/85/f6/IB-IB20002_200x200.png "TPOR Reporter Assay System [Human]")
TPOR Reporter Assay System [Human]
Artikelnummer: IB-IB20002
This assay utilizes proprietary human cells that provide constitutive expression fo the Human Thrombopoietin Receptor (TPOR). TPOR, also known as MPL or CD110, is a member of the type I cytokine receptor superfamily. Thrombopoietin (TPO), the physiological activator of TPOR, is a glycoprotein that regulates...
| Schlagworte: | MPL, TPOR, CD110, TPO-R, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
Anti-MPL / Thrombopoietin Receptor (N-Terminal Region)
Artikelnummer: NSJ-F54100-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Myeloproliferative leukemia protein (MPL) is the receptor for Thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [UniProt] Protein function: Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and...
| Schlagworte: | Anti-MPL, Anti-TPOR, Anti-TPO-R, Anti-CD110, Anti-Proto-oncogene c-Mpl, Anti-Thrombopoietin receptor,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Thrombopoietin receptor (MPL), partial, human, recombinant
Artikelnummer: CSB-EP014755HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 26-491aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QDVSLLASDS EPLKCFSRTF EDLTCFWDEE EAAPSGTYQL LYAYPREKPR ACPLSSQSMP HFGTRYVCQF PDQEEVRLFF PLHLWVKNVF LNQTRTQRVL FVDSVGLPAP PSIIKAMGGS QPGELQISWE...
| Schlagworte: | MPL, TPOR, TPO-R, CD110, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 56.5 kD |
ab 219,00 €
Thrombopoietin receptor (MPL), partial, human, recombinant
Artikelnummer: CSB-YP014755HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 26-491aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QDVSLLASDS EPLKCFSRTF EDLTCFWDEE EAAPSGTYQL LYAYPREKPR ACPLSSQSMP HFGTRYVCQF PDQEEVRLFF PLHLWVKNVF LNQTRTQRVL FVDSVGLPAP PSIIKAMGGS QPGELQISWE...
| Schlagworte: | MPL, TPOR, TPO-R, CD110, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 54.5 kD |
ab 242,00 €
Human c-MPL Protein, hFc Tag
Artikelnummer: DIM-PME100588.10
Recombinant Human c-MPL with C-terminal human Fc tag. c-MPL(Gln26-Ala490) hFc(Glu99-Ala330), Protein function: Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [The UniProt...
| Schlagworte: | C-MPL, CD110, MPLV, THCYT2, THPOR, TPOR |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 78.5 kD |
ab 120,00 €
Anti-MPL
Artikelnummer: CSB-PA005848.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MPL, Anti-TPOR, Anti-TPO-R, Anti-CD110, Anti-Proto-oncogene c-Mpl, Anti-Thrombopoietin receptor,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €