Tioxolone

Tioxolone is an inhibitor of carbonic anhydrase I (CAI, Ki = 91 nM). It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV (Kis = 4,930-9,040 nM). Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes, yeasts, and molds.Formal Name: 6-hydroxy-1,3-benzoxathiol-2-one. CAS Number: 4991-65-5. Synonyms: Thioxolone. Molecular Formula: C7H4O3S. Formula Weight: 168.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:9): 0.1 mg/ml. lambdamax: 233 nm. SMILES: O=C1OC2=CC(O)=CC=C2S1. InChi Code: InChI=1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H. InChi Key: SLYPOVJCSQHITR-UHFFFAOYSA-N.