TG46

TG46 is an inhibitor of JAK2 (IC50 = 12.5 µM).Formal Name: N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-benzenesulfonamide. CAS Number: 936091-15-5. Molecular Formula: C26H34N6O3S. Formula Weight: 510.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml, Ethanol: Slightly Soluble: 0.1-1 mg/ml. SMILES: O=S(NC(C)(C)C)(C1=CC(NC2=NC(NC3=CC=C(CN4CCOCC4)C=C3)=NC=C2C)=CC=C1)=O. InChi Code: InChI=1S/C26H34N6O3S/c1-19-17-27-25(29-21-10-8-20(9-11-21)18-32-12-14-35-15-13-32)30-24(19)28-22-6-5-7-23(16-22)36(33,34)31-26(2,3)4/h5-11,16-17,31H,12-15,18H2,1-4H3,(H2,27,28,29,30). InChi Key: MMXZBJJTHQWMEN-UHFFFAOYSA-N.