TASIN-1

Description: TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC). Target: APC. Smiles: COc1ccc(cc1)S(=O)(=O)N1CCC(CC1)N1CCC(C)CC1. References: Bai R L, Pettit G R, Hamel E. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. Journal of Biological Chemistry, 1990, 265(28): 17141-17149.