SYM 2081

Description: SYM 2081 is a specific kainate receptor agonist with an IC50 value of 35 nM for [3H]-kainate binding. SYM 2081 depolarizes the muscle and reduces the EPSP amplitude. Target: iGluR. Smiles: [C@@H](C[C@@H](C(O)=O)N)(C(O)=O)C. References: Lee JY, et al. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Nov,150(4):546-57.