Sorafenib tosylate

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
CDX-S0264-G005	5 g		-	-	3 - 9 Werktage*		87,00 €
CDX-S0264-G025	25 g		-	-	3 - 9 Werktage*		349,00 €

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Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and... mehr

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Produktinformationen "Sorafenib tosylate"

Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and 22nM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, Flt-3, c-Kit, FGFR-1 (Flt-2) and RET, involved in neovascularization and tumor progression. It is selective for these kinases over 12 other kinases, including ERK1, MEK1, EGFR, and HER2 (IC50s = >10µM for all). Sorafenib tosylate exerts broad-spectrum anticancer activity and disrupts signaling pathways that are vital for tumor growth and angiogenesis.

Schlagworte:	Sorafenib p-toluenesulfonate, Nexavar, ,BAY 43-9006 mono-p-tosylate, BAY 54-9085
Hersteller:	Chemodex
Hersteller-Nr:	S0264

Eigenschaften

Anwendung:	Kinase inhibitor
MW:	637.03 D
Formel:	C21H16ClF3N4O3 . C7H8SO3
Format:	Solid

Datenbank Information

KEGG ID :

K04366 | Passende Produkte

Handhabung & Sicherheit

Lagerung:	+4°C (protect from light & moisture)
Versand:	+20°C (International: +20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H360FD, H362, H372, H410
P-Sätze:	P202, P260, P263, P264, P273, P308+P313