Sodium 4-Phenylbutyrate-d11

Sodium 4-Phenylbutyrate-d11 is intended for use as an internal standard for the quantification of sodium 4-phenylbutyrate (Cay-11323) by GC- or LC-MS. Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins. It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors. Formulations containing sodium 4-phenylbutyrate have been used for the treatment of urea cycle disorders.Formal Name: benzene-d5-butanoic-d6 acid, monosodium salt. CAS Number: 1392208-11-5. Synonyms: Benzenebutanoic acid-d11, TriButyrate-d11. Molecular Formula: C10D11O2 . Na. Formula Weight: 197.2. Purity: >99% deuterated forms (d1-d11). Formulation: (Request formulation change), A solid. Solubility: DMSO: 25 mM, Water: 100 mM. SMILES: [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1C([2H])([2H])C([2H])([2H])C([2H])([2H])C([O-])=O.[Na+]. InChi Code: InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9,/h1-3,5-6H,4,7-8H2,(H,11,12),/q,+1/p-1/i1D,2D,3D,4D2,5D,6D,7D2,8D2,. InChi Key: VPZRWNZGLKXFOE-HSYGEVHBSA-M.