Selumetinib

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T6218-25mg	25 mg	7 - 10 Werktage*	45,00 €
TGM-T6218-50mg	50 mg	7 - 10 Werktage*	59,00 €
TGM-T6218-100mg	100 mg	7 - 10 Werktage*	76,00 €
TGM-T6218-200mg	200 mg	7 - 10 Werktage*	119,00 €
TGM-T6218-500mg	500 mg	7 - 10 Werktage*	187,00 €
TGM-T6218-1g	1 g	7 - 10 Werktage*	280,00 €

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Description: Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with... mehr

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Produktinformationen "Selumetinib"

Description: Selumetinib (AZD6244) is a MEK1/2 inhibitor that inhibits MEK1 (IC50=14 nM) with potent selectivity and is non-ATP-competitive. Selumetinib has antitumor activity and is used for the treatment of neurofibromatosis type 1 (NF1). Target: ERK, MEK, Apoptosis. Smiles: CN1C=NC2=C(F)C(NC3=CC=C(Br)C=C3Cl)=C(C=C12)C(=O)NOCCO. References: Yeh TC, et al. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor. Clin Cancer Res. 2007 Mar 1,13(5):1576-83.

Schlagworte:	AZD6244, ARRY-142886
Hersteller:	TargetMol
Hersteller-Nr:	T6218

Eigenschaften

Anwendung:	Targets mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (MAP2K1, MEK1)
MW:	457.68 D
Formel:	C17H15BrClFN4O3

Datenbank Information

CAS :	606143-52-6\| Passende Produkte
KEGG ID :	K04368 \| Passende Produkte
Protein Atlas Nr. :	Phosphorylation (other)

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H317, H318, H361, H373, H411
P-Sätze:	P201, P202, P260, P261, P272, P273, P280, P310, P314, P321, P391, P302+P352, P305+P351+P338, P308+P313, P333+P313, P362+P364, P405, P501