Saikosaponin C

Description: Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation. Target: Caspase, Beta Amyloid. Smiles: [H][C@]12CC(C)(C)CCC11COC22C=CC3[C@@]4(C)CCC(C(C)(C)C4CC[C@@]3(C)[C@]2(C)C[C@H]1O)[C@]1(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O. References: Lee TH1, Chang J2, Kim BM3. Saikosaponin C inhibits lipopolysaccharide-induced apoptosis by suppressing caspase-3 activation and subsequent degradation of focal adhesion kinase in human umbilical vein endothelial cells.Biochem Biophys Res Commun. 2014 Mar 14,445(3):615-21.