S32826

Description: S32826 is a highly potent inhibitor of autotaxin, exhibiting an IC50 value of 8.8 nM. It displays comparable inhibitory properties towards various autotaxin isoforms, including alpha, beta, and gamma. Furthermore, S32826 effectively inhibits the release of LPA from adipocytes. Target: Others. Smiles: CCCCCCCCCC CCCC(=O)Nc1ccc(CP(O)(O)=O)cc1. References: Ferry G, et, al. S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool. J Pharmacol Exp Ther. 2008 Dec,327(3):809-19.