Zu "K01122" wurden 82 Artikel gefunden!
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PF-8380
Artikelnummer: Cay12018-25
Autotaxin converts lysophosphatidylcholine to lysophosphatidic acid (LPA), which can mediate changes in cell proliferation, angiogenesis, and cytokine secretion. PF-8380 is a potent inhibitor of autotaxin (IC50 = 2.8 nM in an enzyme assay), the enzyme that converts lysophosphatidylcholine to lysophosphatidic acid...
| Schlagworte: | 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-(3,5-dichlorophenyl)methyl ester-1-piperazinecarboxylic acid |
| Anwendung: | Autotaxin Inhibitor |
| CAS | 1144035-53-9 |
| MW: | 478.3 D |
ab 66,00 €
Anti-ENPP2
Artikelnummer: ABS-OC-713.100
Protein function: Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751, PubMed:26371182, PubMed:27754931, PubMed:14500380, PubMed:12354767,). Major substrate is lysophosphatidylcholine (PubMed:12176993, PubMed:27754931, PubMed:14500380)....
| Schlagworte: | Anti-Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Anti-E-NPP 2, Anti-Autotaxin, Anti-Extracellular... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-ENPP2
Artikelnummer: ABS-KC-3441.100
Protein function: Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751, PubMed:26371182, PubMed:27754931, PubMed:14500380, PubMed:12354767,). Major substrate is lysophosphatidylcholine (PubMed:12176993, PubMed:27754931, PubMed:14500380)....
| Schlagworte: | Anti-Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Anti-E-NPP 2, Anti-Autotaxin, Anti-Extracellular... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
ENPP2 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-02055-500ug
Description: ENPP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is Q9R1E6-1.
| Schlagworte: | PD-Ialpha, Pdnp2, ectonucleotide pyrophosphatase/phosphodiesterase 2, PD-Ialpha, ATX, lysoPLD, E-NPP 2, Npps2 |
| MW: | 96 kD |
ab 397,00 €
ATX inhibitor 16
Artikelnummer: TGM-T64130-100mg
Description: ATX inhibitor 16 is a potent ATX inhibitor (IC50: 0.0021 µM) that exhibits a significant anti-proliferative effect on breast cancer cells. Target: Others. Smiles: C(=N\NC1=NC=2C(S1)=CC=CC2)(\C(F)(F)F)/C=3C=4C(N(CC)C3)=CC=C(C4)C5=NC(CN6CCC(O)CC6)=CS5
| Anwendung: | ATX inhibitor |
| CAS | 2484811-36-9 |
| MW: | 584.68 D |
ab 1.520,00 €
ATX inhibitor 11
Artikelnummer: TGM-T64141-100mg
Description: ATX inhibitor 11 is a potent inhibitor of ATX (autotaxin) (IC50: 2.7 nM). ATX inhibitor 11 alleviates the severity of fibrotic tissue and effectively reduces the deposition of alpha-SMA, a biomarker of fibrosis, in a mouse model of fibrosis. ATX inhibitor 11 can be used to study lung fibrosis. Target:...
| Anwendung: | ATX inhibitor |
| CAS | 2485779-27-7 |
| MW: | 585.65 D |
ab 1.520,00 €
ATX inhibitor 13
Artikelnummer: TGM-T64210-100mg
Description: ATX inhibitor 13 (compound 10c) is an orally active ATX inhibitor (IC50: 3.4 nM) that arrests the cell cycle of RAW264.7 cells in the G2 phase, inhibits cell proliferation and migration, induces apoptosis, and exhibits an inhibitory effect on tumour colony formation. Target: Others. Smiles:...
| Anwendung: | ATX inhibitor |
| CAS | 2485779-34-6 |
| MW: | 596.55 D |
ab 1.520,00 €
ATX inhibitor 20
Artikelnummer: TGM-T63829-100mg
Description: ATX inhibitor 20 is a potent inhibitor of ATX (IC50: 2.3 nM). Target: Others. Smiles: N(C(NCC1=CC=C(F)C=C1)=O)C=2C=3C(N(CC)C2)=CC=C(NC(=O)C4=CC=C(CN5CCC(O)CC5)C=C4)C3
| Anwendung: | ATX inhibitor |
| CAS | 2691937-03-6 |
| MW: | 543.63 D |
ab 1.520,00 €
ATX inhibitor 14
Artikelnummer: TGM-T63845-100mg
Description: ATX inhibitor 14, an indole-based carbamate derivative, is a potent inhibitor (IC50: 0.41 nM) of self-adhesive proteins (ATX) and has shown potential for research in fibrosis-related diseases. Target: Others. Smiles: N(C(OCC1=CC(Cl)=CC(Cl)=C1)=O)C=2C=3C(N(CC)C2)=CC=C(C3)C4=NC(CN5CCOCC5)=CS4
| Anwendung: | ATX inhibitor |
| CAS | 2484811-39-2 |
| MW: | 545.48 D |
ab 1.520,00 €
ATX inhibitor 19
Artikelnummer: TGM-T63904-100mg
Description: ATX inhibitor 19 is a potent inhibitor of ATX (IC50: 156 nM). Target: Others. Smiles: N(C(NCC1=CC=C(Cl)C=C1)=O)C=2C=3C(N(CC)C2)=CC=C(C3)C4=NC(CN5CCN(CCO)CC5)=CS4
| Anwendung: | ATX inhibitor |
| CAS | 2691937-01-4 |
| MW: | 553.12 D |
ab 1.520,00 €
ATX inhibitor 9
Artikelnummer: TGM-T63325-100mg
Description: ATX inhibitor 9 is a thickened heteroaryl derivative compound and a potent inhibitor of ATX. Among them Autotaxin (ATX), also known as ENPP2, is a secreted enzyme highly expressed mainly in lung cancer cells, bronchial epithelial cells and alveolar macrophages.ATX inhibitor 9 has research potential for...
| Anwendung: | ATX inhibitor |
| CAS | 2640300-87-2 |
| MW: | 493.52 D |
ab 1.520,00 €
ATX inhibitor 8
Artikelnummer: TGM-T63612-100mg
Description: ATX inhibitor 8 is an inhibitor of the autocrine motor factor Autotaxin (ATX). Target: Others. Smiles: C(C(=O)N1CC2=C(CC1)NN=N2)N3C=C(C(=N3)C=4C=CN=CC4)C=5C=NC(NC6CC=7C(C6)=CC=CC7)=NC5
| Anwendung: | ATX inhibitor |
| CAS | 2156656-37-8 |
| MW: | 518.57 D |
ab 1.520,00 €