S 07662

An inverse agonist of CAR, stabilizes the ligand-binding domain of human CAR, increases the recruitment of NCOR, and reduces CAR activity (IC50 = 0.7 µM for the human receptor in a cell-based assay). SMILES: CC1=C(CNC(NCC2=CC=CS2)=O)C3=C(O1)C=CC=C3. InChi Code: InChI=1S/C16H16N2O2S/c1-11-14(13-6-2-3-7-15(13)20-11)10-18-16(19)17-9-12-5-4-8-21-12/h2-8H,9-10H2,1H3,(H2,17,18,19). InChi Key: UITFWLJMEZPXOF-UHFFFAOYSA-N