Zu "K08541" wurden 33 Artikel gefunden!
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Rat CAR (Constitutive Androstane Receptor) ELISA Kit
Artikelnummer: ELK-ELK7571.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CAR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CAR. Next, Avidin...
| Schlagworte: | CAR, Car, Nr1i3, Constitutive androstane receptor, Nuclear receptor subfamily 1 group I member 3 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human CAR (Constitutive Androstane Receptor) ELISA Kit
Artikelnummer: ELK-ELK5321.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CAR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CAR. Next,...
| Schlagworte: | CAR, NR1I3, Constitutive active response, Orphan nuclear receptor MB67, Constitutive androstane receptor, Constitutive... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Z-CITCO
Artikelnummer: Cay39172-1
Z-CITCO is an agonist of the constitutive androstane receptor (CAR, EC50 = 3.9 µM for the human receptor in a reporter assay) and the cis isomer of the CAR agonist CITCO (Cay-16027).Formal Name: [C(Z)]-6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime. CAS Number:...
| Schlagworte: | [C(Z)]-6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime |
| Anwendung: | CAR agonist |
| CAS | 2583138-04-7 |
| MW: | 436.7 D |
ab 40,00 €
TCPOBOP
Artikelnummer: Cay14140-5
The mouse constitutive androstane receptor (mCAR), with the retinoid X receptor, binds to the retinoic acid response element to upregulate the expression of proteins that metabolize xenobiotics. TCPOBOP is an agonist for mCAR (EC50 = 20 nM) that is effective for the mouse receptor but not for human or rat CAR...
| Schlagworte: | 2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro]-pyridine |
| Anwendung: | Mouse CAR agonist |
| CAS | 76150-91-9 |
| MW: | 402.1 D |
ab 60,00 €
CITCO
Artikelnummer: Cay16027-10
CITCO is an agonist of human CAR (EC50 = 49 nM). It induces nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. CITCO less potently activates human pregnane X receptor (EC50 = 3 µM) and has no detectable activity on...
| Schlagworte: | O-[(3,4-dichlorophenyl)methyl]oxime 6-(4-chlorophenyl)-imidazo[2,1-b]thiazole-5-carboxaldehyde |
| Anwendung: | CAR agonist |
| CAS | 338404-52-7 |
| MW: | 436.7 D |
ab 97,00 €
CINPA1
Artikelnummer: Cay29110-1
CINPA1 is a constitutive androstane receptor (CAR) antagonist (IC50 = 70 nM in a reporter assay). It is selective for CAR over the nuclear receptors GR, FXR, LXRalpha, LXRbeta, PPARgamma, RXRalpha, and RXRbeta at 18 µM, but also antagonizes the human pregnane X receptor (PXR, IC50 = 6.6 µM). CINPA1 (0.3-5 µM)...
| Schlagworte: | [5-[(diethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]-carbamic acid, ethyl ester |
| Anwendung: | Constitutive androstane receptor (CAR) antagonist |
| CAS | 102636-74-8 |
| MW: | 395.5 D |
ab 43,00 €
Anti-NR1I3
Artikelnummer: ARG57440.100
Protein function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. [The...
| Schlagworte: | Anti-CAR, Anti-NR1I3, Anti-Constitutive active response, Anti-Orphan nuclear receptor MB67, Anti-Constitutive androstane... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Human CAR / NR1I3 ELISA Kit
Artikelnummer: G-HUFI01793.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Mouse CAR / NR1I3 ELISA Kit
Artikelnummer: G-MOFI00541.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
CAR3 (human) Reporter Assay Kit
Artikelnummer: IB-IB00902
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human constitutive androstane receptor, isoform 3 (NR1I3), a ligand-dependent transcription factor commonly referred to as CAR3. These reporter cells utilize a modified...
| Schlagworte: | CAR, NR1I3, Constitutive active response, Orphan nuclear receptor MB67, Constitutive androstane receptor, Constitutive... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
CAR3 (human) Reporter Assay Kit
Artikelnummer: IB-IB00901
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human constitutive androstane receptor, isoform 3 (NR1I3), a ligand-dependent transcription factor commonly referred to as CAR3. These reporter cells utilize a modified...
| Schlagworte: | CAR, NR1I3, Constitutive active response, Orphan nuclear receptor MB67, Constitutive androstane receptor, Constitutive... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
CAR (Mouse) Reporter Assay System
Artikelnummer: IB-M00901
Protein function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. [The...
| Schlagworte: | Car, CAR, Nr1i3, Orphan nuclear receptor MB67, Constitutive androstane receptor, Nuclear receptor subfamily 1 group I... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.448,00 €