RMC-4630

RMC-4630 is an allosteric inhibitor of Src homology region 2 domain-containing phosphatase 2 (SHP-2).Formal Name: 6-[(2-amino-3-chloro-4-pyridinyl)thio]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-5-methyl-2-pyrazinemethanol. CAS Number: 2172652-48-9. Synonyms: SAR442720. Molecular Formula: C20H27ClN6O2S. Formula Weight: 451.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly Soluble, DMSO: Soluble, Water: Slightly Soluble. SMILES: N[C@H]1C2(CO[C@H]1C)CCN(C3=NC(C)=C(N=C3CO)SC4=CC=NC(N)=C4Cl)CC2. InChi Code: InChI=1S/C20H27ClN6O2S/c1-11-19(30-14-3-6-24-17(23)15(14)21)26-13(9-28)18(25-11)27-7-4-20(5-8-27)10-29-12(2)16(20)22/h3,6,12,16,28H,4-5,7-10,22H2,1-2H3,(H2,23,24)/t12-,16+/m0/s1. InChi Key: HISJAYUQVHMWTA-BLLLJJGKSA-N.