Rezvilutamide

Rezvilutamide is a non-steroidal androgen receptor antagonist. It reduces secretion of prostate-specific androgen (PSA) from LNCaP prostate cancer cells (IC50 = 22 nM) and reduces proliferation of the same cells (IC50 = 33 nM). Formulations containing rezvilutamide have been used in the treatment of prostate cancer.. SMILES: N#CC(C=CC(N1C(C(C)(C)N(C1=S)C2=CC=C(OC[C@H](CO)O)C=C2)=O)=C3)=C3C(F)(F)F. InChi Code: InChI=1S/C22H20F3N3O4S/c1-21(2)19(31)27(15-4-3-13(10-26)18(9-15)22(23,24)25)20(33)28(21)14-5-7-17(8-6-14)32-12-16(30)11-29/h3-9,16,29-30H,11-12H2,1-2H3/t16-/m0/s1. InChi Key: KRBMOYIWQCZVHA-INIZCTEOSA-N