Zu "K08557" wurden 397 Artikel gefunden!
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AR (human) Reporter Assay Kit
Artikelnummer: IB-IB03001
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
NEU
Enzalutamide-d3
Artikelnummer: Cay45044-1
An internal standard for the quantification of enzalutamide by GC- or LC-MS. SMILES: S=C1N(C2=CC(F)=C(C=C2)C(NC([2H])([2H])[2H])=O)C(C)(C(N1C3=CC(C(F)(F)F)=C(C=C3)C#N)=O)C. InChi Code:...
| Schlagworte: | 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)-benzamide |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, non-steroidal androgen receptor antagonist |
| CAS | 1443331-82-5 |
| MW: | 467.46 D |
535,00 €
NEU
MK-0773
Artikelnummer: Cay43202-1
MK-0773 is a selective androgen receptor modulator (SARM). It selectively binds to the androgen receptor (AR, IC50 = 6.6 nM) over the glucocorticoid and progesterone receptors (IC50s = >2 µM for both). It is a partial agonist of AR that increases AR-dependent transcription in a reporter assay using MDA-MB-453 cells...
| Schlagworte: | PF-05314882, (4aS,4bS,6aS,7S,9aS,9bS,11aR)-3-fluoro-2,4a,4b,5,6,6a,7,... |
| Anwendung: | Selective androgen receptor modulator (SARM) |
| CAS | 606101-58-0 |
| MW: | 479.6 D |
ab 105,00 €
NEU
ARD-266
Artikelnummer: Cay45321-1
ARD-266 is a proteolysis-targeting chimera (PROTAC) containing an androgen receptor antagonist conjugated to a VHL ligand via a piperidine-alkyne linker. It induces degradation of the androgen receptor in LNCaP, VCaP, and 22Rv1 prostate cancer cells with half-maximal degradation concentration (DC50) values of 0.54,...
| Schlagworte: | (2S,4R)-N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethyny... |
| Anwendung: | Androgen receptor (AR/NR3C4) degradation driving PROTAC |
| CAS | 2666951-70-6 |
| MW: | 915.53 D |
ab 139,00 €
NEU
Rezvilutamide
Artikelnummer: Cay45332-10
Rezvilutamide is a non-steroidal androgen receptor antagonist. It reduces secretion of prostate-specific androgen (PSA) from LNCaP prostate cancer cells (IC50 = 22 nM) and reduces proliferation of the same cells (IC50 = 33 nM). Formulations containing rezvilutamide have been used in the treatment of prostate...
| Schlagworte: | SHR-3680,... |
| Anwendung: | Non-steroidal androgen receptor antagonist |
| CAS | 1572045-62-5 |
| MW: | 479.47 D |
ab 271,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM1X-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: LNCap cells. Prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | FC, IF, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM1X-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: LNCap cells. Prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | FC, IF, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM2-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: breast or prostate carcinoma., LNCap cells. Human testis. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | FC, IF, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM27-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: Human testis, breast, prostate or prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM27-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: Human testis, breast, prostate or prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €
Anti-Androgen Receptor V7 (Marker of Androgen...
Artikelnummer: NEO-367-RBM22-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Nucleus. Positive Control: Breast, Human testis, prostate or prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
704,00 €
Anti-Androgen Receptor (Marker of Androgen Dependence),...
Artikelnummer: NEO-367-MSM10-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: Breast, LNCap cells. Human testis, prostate or prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4, 559 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €