Zu "K08557" wurden 401 Artikel gefunden!
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AR (human) Reporter Assay Kit
Artikelnummer: IB-IB03001
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
RAD140
Artikelnummer: Cay18773-5
RAD140 is an orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM) that binds to the androgen receptor with a Ki value of 7 nM. At 0.03-0. mg/kg, it has been shown to stimulate muscle weight increase without affecting prostate or seminal vesicle in castrated male rats. At 0.3-1 mg/kg, RAD140...
| Schlagworte: | Testolone, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methyl-benzonitrile |
| Anwendung: | Selective androgen receptor modulator (SARM) |
| CAS | 1182367-47-0 |
| MW: | 393.8 D |
ab 204,00 €
AZD 9750
Artikelnummer: Cay45751-1
AZD 9750 is a proteolysis-targeting chimera (PROTAC) composed of an androgen receptor ligand and a lenalidomide derivative. It induces the degradation of wild-type androgen receptor (AR) and drug-resistant mutant AR containing a leucine-to-histidine substitution at position 702 (ARL702H) with half-maximal...
| Schlagworte: | 4-chloro-7-[(3S)-3-[4-[4-[[4-[1-methyl-6-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)-1H-indol-2-yl]-1-piperidinyl]methyl]-1-p... |
| Anwendung: | Androgen receptor degradation driving PROTAC |
| CAS | 3056515-10-4 |
| MW: | 758.37 D |
ab 669,00 €
Bicalutamide
Artikelnummer: BPS-84096-1
Bicalutamide is an orally active non-steroidal AR (androgen receptor) antagonist. It is of interest in research in prostate cancer. Prostate cancer is the most common cancer found in men in the western world. The disease is characterized by several stages, with androgen and AR (androgen receptor) being crucial for...
| Schlagworte: | AR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Anwendung: | In vitro assays |
| MW: | 430.37 D |
ab 281,00 €
Anti-Androgen Receptor, clone r2F12
Artikelnummer: NSJ-V5924SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
Anti-Androgen Receptor, clone r2F12
Artikelnummer: NSJ-V5924-100UG
0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-Androgen Receptor, clone MSVA-367R
Artikelnummer: NSJ-V6092-100UG
Antibody in 1X PBS with 0.05% BSA, 0.05% sodium azide. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...
| Schlagworte: | Anti-AR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 684,00 €
Testosterone Enanthate (exempt preparation)
Artikelnummer: Cay46044-1
Testosterone enanthate (exempt preparation) (Cay46044) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone enanthate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). It has been found in performance-enhancing drug (PED) samples seized by law...
| Schlagworte: | NSC 17591, 17beta-[(1-oxoheptyl)oxy]-androst-4-en-3-one |
| Anwendung: | Analytical reference standard, anabolic androgenic steroid |
| CAS | 315-37-7 |
| MW: | 400.6 D |
299,00 €
Testosterone Cypionate (exempt preparation)
Artikelnummer: Cay46045-1
Testosterone cypionate (exempt preparation) (Cay46045) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone cypionate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). It has been detected in hair samples from competition athletes and plasma samples...
| Schlagworte: | NSC 9157, 17beta-(3-cyclopentyl-1-oxopropoxy)-androst-4-en-3-one |
| Anwendung: | Analytical reference standard, anabolic androgenic steroid |
| CAS | 58-20-8 |
| MW: | 412.61 D |
299,00 €
Testosterone Isobutyrate
Artikelnummer: Cay41937-1
Testosterone isobutyrate (Cay41937) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone isobutyrate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). Testosterone isobutyrate is regulated as a Schedule III compound in the United States. This product...
| Schlagworte: | Testosterone 17-isobutyrate, Testosterone 2-methylpropanoate, 17beta-(2-methyl-1-oxopropoxy)-androst-4-en-3-one |
| Anwendung: | Analytical reference standard, anabolic androgenic steroid |
| CAS | 1169-49-9 |
| MW: | 358.51 D |
ab 249,00 €
ARD-266
Artikelnummer: Cay45321-1
ARD-266 is a proteolysis-targeting chimera (PROTAC) containing an androgen receptor antagonist conjugated to a VHL ligand via a piperidine-alkyne linker. It induces degradation of the androgen receptor in LNCaP, VCaP, and 22Rv1 prostate cancer cells with half-maximal degradation concentration (DC50) values of 0.54,...
| Schlagworte: | (2S,4R)-N-[(1S)-3-[4-[2-[4-[[[trans-3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]amino]carbonyl]phenyl]ethyny... |
| Anwendung: | Androgen receptor (AR/NR3C4) degradation driving PROTAC |
| CAS | 2666951-70-6 |
| MW: | 915.53 D |
ab 139,00 €
Rezvilutamide
Artikelnummer: Cay45332-10
Rezvilutamide is a non-steroidal androgen receptor antagonist. It reduces secretion of prostate-specific androgen (PSA) from LNCaP prostate cancer cells (IC50 = 22 nM) and reduces proliferation of the same cells (IC50 = 33 nM). Formulations containing rezvilutamide have been used in the treatment of prostate...
| Schlagworte: | SHR-3680,... |
| Anwendung: | Non-steroidal androgen receptor antagonist |
| CAS | 1572045-62-5 |
| MW: | 479.47 D |
ab 271,00 €