Reboxetine (mesylate)

Reboxetine is an antidepressant compound that selectively inhibits norepinephrine uptake (IC50s = 8.2 and 1,070 nM for norepinephrine and serotonin transporters, respectively). It displays greater than 1,000-fold affinity for binding rat norepinephrine receptors compared to serotonin, histamine, acetylcholine, or dopamine receptors (Kis = 1.1, 129, 1,400, 3,900, and >10,000 nM, respectively).Formal Name: (2R)-rel-2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-morpholine, methanesulfonate. CAS Number: 98769-84-7. Synonyms: FCE 20124, PNU 155950E. Molecular Formula: C19H23NO3 . CH3SO3H. Formula Weight: 409.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 276 nm. SMILES: CCOC1=CC=CC=C1OC(C2OCCNC2)C3=CC=CC=C3.CS(=O)(O)=O. InChi Code: InChI=1S/C19H23NO3.CH4O3S/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18,1-5(2,3)4/h3-11,18-20H,2,12-14H2,1H3,1H3,(H,2,3,4). InChi Key: CGTZMJIMMUNLQD-UHFFFAOYSA-N.