Protein kinase inhibitors 1

Description: Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. Target: DYRK, Others. Smiles: O=C1C(=CC(C=C2SC(=O)NC2=O)=CN1)C=3C=CC(=NC3)N4CCNCC4. References: Miduturu CV, et al. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinaseinhibitors. Chem Biol. 2011 Jul 29,18(7):868-79.