PKCbeta inhibitor 1

Description: PKCbeta inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCbeta1 and PKCbeta2, respectively). Target: Apoptosis, PKC. Smiles: O=C1NC(=O)C(=C1Nc1ccccc1)c1cn(CCCn2ccnc2)c2ccccc12. References: Saba N S , Levy L S . Protein Kinase C-Beta Inhibition Induces Apoptosis and Inhibits Cell Cycle Progression in Acquired Immunodeficiency Syndrome-Related Non-Hodgkin Lymphoma Cells[J]. Journal of Investigative Medicine, 2012, 60(1):29-.