PFM01

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay36574-5	5 mg	-	6 - 10 Werktage*	74,00 €
Cay36574-10	10 mg	-	6 - 10 Werktage*	133,00 €
Cay36574-25	25 mg	-	6 - 10 Werktage*	309,00 €

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PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein... mehr

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Produktinformationen "PFM01"

PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated by non-homologous end-joining (NHEJ) in H1299 dA3 cells.Formal Name: 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone. CAS Number: 1558598-41-6. Molecular Formula: C14H15NO2S2. Formula Weight: 293.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 29.3 mg/ml. SMILES: OC(C=C1)=CC=C1/C=C2SC(N(CC(C)C)C\2=O)=S. InChi Code: InChI=1S/C14H15NO2S2/c1-9(2)8-15-13(17)12(19-14(15)18)7-10-3-5-11(16)6-4-10/h3-7,9,16H,8H2,1-2H3/b12-7-. InChi Key: GPURHDUTZUYAFI-GHXNOFRVSA-N.

Schlagworte:	5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone
Hersteller:	Cayman Chemical
Hersteller-Nr:	36574

Eigenschaften

Anwendung:	Mre11 endonuclease activity inhibitor
MW:	293.4 D
Formel:	C14H15NO2S2
Reinheit:	>98%
Format:	Solid

Datenbank Information

CAS :	1558598-41-6\| Passende Produkte
KEGG ID :	K10865 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H315, H319
P-Sätze:	P264, P280, P321, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364