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Anti-Recombinant MRE11, clone 6B9
Anti-Recombinant MRE11, clone 6B9

Artikelnummer: E-AN301268L.100

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
Schlagworte: Anti-MRE11, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic recombination 11 homolog 1, Anti-Double-strand break...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 257,00 €
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Mirin
Mirin

Artikelnummer: Cay13208-10

Mirin is an inhibitor of the Mre11/Rad50/Nbs1 (MRN) complex, which functions as a DNA damage sensor and activates the DNA repair enzyme ataxia-telangiectasia mutated kinase (ATM). It inhibits phosphorylation of H2AX induced by DNA containing dsDNA breaks (DSBs), indicating decreased ATM activation, with an IC50...
Schlagworte: 2-amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
Anwendung: MRN complex inhibitor
CAS 299953-00-7
MW: 220.3 D
ab 69,00 €
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Anti-Mre11
Anti-Mre11

Artikelnummer: A303-998A-T

Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 165,00 €
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Anti-Mre11
Anti-Mre11

Artikelnummer: 600-401-872

Protein function: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. [The UniProt Consortium]
Schlagworte: Anti-MRE11, Anti-YMR224C, Anti-Double-strand break repair protein MRE11
Anwendung: ELISA, ChIP, WB
Wirt: Rabbit
Spezies-Reaktivität: s.cerivisiae
733,00 €
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Anti-Mre11
Anti-Mre11

Artikelnummer: 600-401-896

Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by...
Schlagworte: Anti-Mre11, Anti-Mre11a, Anti-MmMRE11A, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog...
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: mouse
733,00 €
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Anti-MRE11
Anti-MRE11

Artikelnummer: NSJ-RQ4229

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic...
Anwendung: WB, IHC (paraffin), ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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Anti-MRE11A
Anti-MRE11A

Artikelnummer: E-AB-11403.120

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic...
Anwendung: WB, IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 89,00 €
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Anti-MRE11A
Anti-MRE11A

Artikelnummer: E-AB-15211.120

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic...
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 89,00 €
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Anti-Mre11
Anti-Mre11

Artikelnummer: ARG59559.100

Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289). The complex possesses single-strand endonuclease...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog 1, Anti-Meiotic...
Anwendung: IHC (paraffin), WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
658,00 €
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Anti-MRE11
Anti-MRE11

Artikelnummer: ATA-HPA002691.100

Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289). The complex possesses single-strand endonuclease...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog 1, Anti-Meiotic...
Anwendung: ICC, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 330,00 €
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PFM01
PFM01

Artikelnummer: Cay36574-10

PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated...
Schlagworte: 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone
Anwendung: Mre11 endonuclease activity inhibitor
CAS 1558598-41-6
MW: 293.4 D
ab 74,00 €
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Anti-MRE11
Anti-MRE11

Artikelnummer: NSJ-RQ6658

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein...
Schlagworte: Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic...
Anwendung: WB, IHC (paraffin), IF, FC, Direct ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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