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Zu "K10865" wurden 58 Artikel gefunden!
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Artikelnummer: E-AN301268L.100
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
| Schlagworte: | Anti-MRE11, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic recombination 11 homolog 1, Anti-Double-strand break... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 257,00 €
Artikelnummer: Cay13208-10
Mirin is an inhibitor of the Mre11/Rad50/Nbs1 (MRN) complex, which functions as a DNA damage sensor and activates the DNA repair enzyme ataxia-telangiectasia mutated kinase (ATM). It inhibits phosphorylation of H2AX induced by DNA containing dsDNA breaks (DSBs), indicating decreased ATM activation, with an IC50...
| Schlagworte: | 2-amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone |
| Anwendung: | MRN complex inhibitor |
| CAS | 299953-00-7 |
| MW: | 220.3 D |
ab 69,00 €
Artikelnummer: A303-998A-T
Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: 600-401-872
Protein function: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. [The UniProt Consortium]
| Schlagworte: | Anti-MRE11, Anti-YMR224C, Anti-Double-strand break repair protein MRE11 |
| Anwendung: | ELISA, ChIP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | s.cerivisiae |
733,00 €
Artikelnummer: 600-401-896
Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by...
| Schlagworte: | Anti-Mre11, Anti-Mre11a, Anti-MmMRE11A, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
733,00 €
Artikelnummer: NSJ-RQ4229
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic... |
| Anwendung: | WB, IHC (paraffin), ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: E-AB-11403.120
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: E-AB-15211.120
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: ARG59559.100
Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289). The complex possesses single-strand endonuclease...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog 1, Anti-Meiotic... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Artikelnummer: ATA-HPA002691.100
Protein function: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547, PubMed:29670289). The complex possesses single-strand endonuclease...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog 1, Anti-Meiotic... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 330,00 €
Artikelnummer: Cay36574-10
PFM01 is an inhibitor of the endonuclease activity of the double-strand break repair protein Mre11. It decreases the number of chromosomal breaks in 1BR3 fibroblasts induced by knockdown of BRCA2. PFM01 (50 µM) reduces homologous recombination-mediated DNA repair in DR-GFP U2OS cells and enhances DNA repair mediated...
| Schlagworte: | 5Z-[(4-hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone |
| Anwendung: | Mre11 endonuclease activity inhibitor |
| CAS | 1558598-41-6 |
| MW: | 293.4 D |
ab 74,00 €
Artikelnummer: NSJ-RQ6658
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein...
| Schlagworte: | Anti-HNGS1, Anti-MRE11 homolog A, Anti-MRE11 homolog 1, Anti-Meiotic recombination 11 homolog A, Anti-Meiotic... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €