Pemirolast (potassium salt)

Pemirolast is a histamine H1 receptor antagonist and a mast cell stabilizer that prevents the release of histamine. It also blocks the release of substance P, neurokinin A, and calcitonin gene-related peptide from sensory nerves. Pemirolast has been used for the treatment of allergic conjunctivitis.Formal Name: 9-methyl-3-(2H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one, monopotassium salt. CAS Number: 100299-08-9. Synonyms: BMY 26517, TBX. Molecular Formula: C10H7N6O . K. Formula Weight: 266.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.1 mg/ml, DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 211, 259, 364 nm. SMILES: CC1=CC=CN2C1=NC=C(C3=NN=N[N-]3)C2=O.[K+]. InChi Code: InChI=1S/C10H7N6O.K/c1-6-3-2-4-16-9(6)11-5-7(10(16)17)8-12-14-15-13-8,/h2-5H,1H3,/q-1,+1. InChi Key: NMMVKSMGBDRONO-UHFFFAOYSA-N.