PE(18:1(9Z)/0:0)

Description: PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner. PE(18:1(9Z)/0:0) increases the production of IL-4 and IL-2, but not IFN-gamma. In mouse serum, PE(18:1(9Z)/0:0) (1 µg/animal) induces the T helper 2 response. PE(18:1(9Z)/0:0) levels increase in interscapular brown adipose tissue in mice following three-day cold exposure. Target: Endogenous Metabolite. Smiles: CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)OCCN. References: Liu B, Guo, et al. HSerum metabolomics analysis of deficiency pattern and excess pattern in patients with rheumatoid arthritis.Chin Med. 2022 Jun 15,17(1):71.