PDDC inhibitor

Description: PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is a selective and highly potent nSMase2 inhibitor. Target: HIV Protease. Smiles: CC=1N=C2N(C1C3=CC(OC)=C(OC)C=C3)N=C(C)C=C2N4C[C@H](NC(OC5=CC=CC=C5)=O)CC4. References: Siew ZY, et al. Fighting nature with nature: antiviral compounds that target retroviruses. Arch Microbiol. 2024 Feb 28,206(3):130.