Paclitaxel C

Paclitaxel C is a taxoid and derivative of paclitaxel (Cay-10461) that has been found in T. cuspidata and an inhibitor of microtubule depolymerization. It inhibits calcium-induced microtubule depolymerization in vitro when used at a concentration of 10 µM.Formal Name: (alphaR,betaS)-alpha-hydroxy-beta-[(1-oxohexyl)amino]-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester. CAS Number: 153415-45-3. Synonyms: Taxol C, Taxuyunnanine A. Molecular Formula: C46H57NO14. Formula Weight: 847.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: soluble. SMILES: C[C@]1(C([C@@H](C2=C(C)[C@@H](OC([C@H](O)[C@H](C3=CC=CC=C3)NC(CCCCC)=O)=O)C[C@]4(O)C2(C)C)OC(C)=O)=O)[C@@]([C@@H]4OC(C5=CC=CC=C5)=O)([H])[C@@]([C@@]6([H])C[C@@H]1O)(CO6)OC(C)=O. InChi Code: InChI=1S/C46H57NO14/c1-8-9-12-21-33(51)47-35(28-17-13-10-14-18-28)36(52)42(55)59-30-23-46(56)40(60-41(54)29-19-15-11-16-20-29)38-44(7,31(50)22-32-45(38,24-57-32)61-27(4)49)39(53)37(58-26(3)48)34(25(30)2)43(46,5)6/h10-11,13-20,30-32,35-38,40,50,52,56H,8-9,12,21-24H2,1-7H3,(H,47,51)/t30-,31-,32+,35-,36+,37+,38-,40-,44+,45-,46+/m0/s1. InChi Key: BEHTXUBGUDGCNQ-IEAAAIHOSA-N. Origin: Synthetic.