Zu "K07374" wurden 332 Artikel gefunden!
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Anti-Alpha Tubulin / TUBA1C
Artikelnummer: NSJ-FY12945
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. Alpha Tubulin antibody detects Alpha tubulin, a fundamental structural component of microtubules, which are integral parts of the cytoskeleton responsible for cell shape, intracellular transport, and mitotic spindle formation. The UniProt...
| Schlagworte: | Anti-TUBA1C, Anti-Alpha-tubulin 6, Anti-Tubulin alpha-6 chain, Anti-Tubulin alpha-1C chain, Alpha Tubulin Antibody / TUBA1C |
| Anwendung: | WB, IHC, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-Alpha Tubulin (acetyl K40) / TUBA1B/TUBA4A, clone 31T79
Artikelnummer: NSJ-FY12718
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Alpha Tubulin (acetyl K40) antibody detects alpha tubulin specifically when acetylated at lysine 40. Alpha tubulin, encoded by multiple genes including TUBA1A, TUBA3C, and TUBA4A, is one of the two...
| Schlagworte: | Anti-TUBA1B, Anti-Tubulin K-alpha-1, Anti-Tubulin alpha-1B chain, Anti-Alpha-tubulin ubiquitous, Anti-Tubulin... |
| Anwendung: | WB, IHC, ICC, IF, IP, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M025
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
Paclitaxel
Artikelnummer: Cay10461-5
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values...
| Schlagworte: | NSC 125973, betaS-(benzoylamino)-alphaR-hydroxy-benzenepropanoic acid,... |
| Anwendung: | Apotosis inducer |
| CAS | 33069-62-4 |
| MW: | 853.9 D |
ab 53,00 €
Mertansine-13C-d3
Artikelnummer: Cay44406-1
Mertansine-13C-d3 is intended for use as an internal standard for the quantification of mertansine (Cay-22483) by GC- or LC-MS. Mertansine is a synthetic maytansinoid antimitotic agent. It is cytotoxic to KB epidermoid carcinoma and SK-BR-3 breast cancer cells (IC50 = 1. nM for both). Mertansine has commonly been...
| Schlagworte: | DM1-13C-d3, Emtansine-13C-d3 |
| Anwendung: | Internal standard, GC-MS, LC-MS, quantification, antimitotic agent |
| MW: | 742.3 D |
815,00 €
Anti-Tubulin, alpha
Artikelnummer: 600-401-880
Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]
| Schlagworte: | Anti-TUBA1B, Anti-Tubulin K-alpha-1, Anti-Tubulin alpha-1B chain, Anti-Alpha-tubulin ubiquitous, Anti-Tubulin... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
590,00 €
Anti-acetyl-alpha-Tubulin, clone TEU318
Artikelnummer: AG-20B-0068-C100
Detects K40 acetylation of alpha-tubulin, signal specifically increased by modification with tubulin acetyl transferase alpha-TAT1. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule...
| Schlagworte: | Anti-acetyl-Tubulin alpha chain, (acetylated Lys40, K40) |
| Anwendung: | WB, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
374,00 €
Docetaxel (hydrate)
Artikelnummer: Cay11637-5
Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel (Cay-10461). It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 µM and is cytotoxic to J774.2 cells (EC50 = 0.05 µM). In vivo, docetaxel inhibits tumor growth in several cancer models,...
| Schlagworte: | NSC 628503, RP 56976, Taxotel, (alphaR,betaS)-beta-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic... |
| Anwendung: | Microtubule inhibitor |
| CAS | 700367-34-6 |
| MW: | 807.9 D |
ab 68,00 €
Colchicine
Artikelnummer: Cay9000760-100
Colchicine is an inhibitor of microtubule polymerization (IC50 = 3.2 µM) that binds to tubulin, which disrupts spindle formation during mitosis. It inhibits growth of MCF-7 human breast carcinoma cells with an IC50 value of 13 nM. Colchicine has anti-inflammatory activity, inhibiting neutrophil motility and activity...
| Schlagworte: | N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide |
| Anwendung: | Microtubule polymerization inhibitor |
| CAS | 64-86-8 |
| MW: | 399.4 D |
ab 25,00 €
Anti-detyrosinated-alpha-Tubulin (human), Rabbit...
Artikelnummer: REV-31-1335-00-R100
Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]
| Schlagworte: | Anti-detyrosinated-TUBA2, Anti-detyrosinated-TUBA3C, anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444),... |
| Anwendung: | WB, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
541,00 €
Nocodazole
Artikelnummer: AG-CR1-0019-M005
Microtubule inhibitor, Antitumor compound, Mitosis inhibitor, Arrests the cell cycle at G2/M phase, Promotes tubulin depolymerization, Induces fragmentation of the Golgi complex, Inhibits the T cell antigen receptor, Stimulates the intrinsic GTPase activity of tubulin, Activates the JNK/SAPK signaling pathway,...
| Schlagworte: | Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate |
| Anwendung: | Microtubule inhibitor, Mitosis inhibitor |
| CAS | 31430-18-9 |
| MW: | 301,3 D |
ab 39,00 €
Nocodazole
Artikelnummer: Cay13857-50
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Schlagworte: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Anwendung: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
ab 54,00 €