p-iodo-Clonidine (hydrochloride)

p-iodo-Clonidine is a partial agonist of the alpha2-adrenergic receptor, minimally inhibiting adenylate cyclase through this Gi protein-coupled receptor although it binds avidly (Ki = 1.0 nM). It potentiates platelet aggregation by ADP (EC50 = 1.5 µM) and inhibits epinephrine-induced aggregation (IC50 = 5.1 µM).Formal Name: N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride. CAS Number: 108294-57-1. Molecular Formula: C9H8Cl2IN3 . HCl. Formula Weight: 392.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.25 mg/ml, DMSO: 1 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 216, 247 nm. SMILES: ClC1=CC(I)=CC(Cl)=C1NC2=NCCN2.Cl. InChi Code: InChI=1S/C9H8Cl2IN3.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9,/h3-4H,1-2H2,(H2,13,14,15),1H. InChi Key: ULCGXOSKNHMYAX-UHFFFAOYSA-N.