OGG1-IN-O8

OGG1-IN-O8 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1, IC50 = 0.35 µM). It is selective for OGG1 over Nei-like DNA glycosylase 1 (NEIL1), endonuclease III homolog 1 (NTH1), and formamidopyrimidine DNA glycosylase (Fpg) at 50 µM.Formal Name: 3,4-dichloro-benzo[b]thiophene-2-carboxylic acid, hydrazide. CAS Number: 350997-39-6. Molecular Formula: C9H6Cl2N2OS. Formula Weight: 261.1. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 5mg/mL, DMSO: 10mg/mL, DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL. lambdamax: 237, 284, 311 nm. SMILES: ClC1=C(C(Cl)=C(C(NN)=O)S2)C2=CC=C1. InChi Code: InChI=1S/C9H6Cl2N2OS/c10-4-2-1-3-5-6(4)7(11)8(15-5)9(14)13-12/h1-3H,12H2,(H,13,14). InChi Key: HSSHUDKWJRJKPV-UHFFFAOYSA-N.