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Zu "K03660" wurden 46 Artikel gefunden!
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NEU
Artikelnummer: Cay43043-10
TH10785 is an 8-oxoguanine DNA glycosylase 1 (OGG1) activator. It increases OGG1-mediated excision of 8-oxoguanine (8-hydroxyguanine, Cay-89290) in duplex oligonucleotides when used at a concentration of 10 µM. TH10785 (10, 30, or 100 µM) inhibits oxidative damage in A549 cells induced by paraquat (Cay-38521). It...
Schlagworte: | N-cyclohexyl-2-cyclopropyl-4-quinazolinamine |
Anwendung: | OGG1 activator |
CAS | 1002801-51-5 |
MW: | 267.38 D |
ab 90,00 €
Artikelnummer: TGM-T8336-100mg
Description: OGG1-IN-08 (OGG1-IN-O8) is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1,IC50 : 0.35 µM). Target: Others. Smiles: NNC(=O)C1=C(Cl)C2=C(Cl)C=CC=C2S1. References: Lloyd, R.S., Mccullough, A.K., and Donley, N. Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1). (2016).
Schlagworte: | OGG1-IN-O8 |
Anwendung: | OGG1 inhibitor |
CAS | 350997-39-6 |
MW: | 261.13 D |
ab 48,00 €
Artikelnummer: TGM-T9119-100mg
Description: SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor that regulates inflammatory responses during Pseudomonas aeruginosa infection. Target: Others. Smiles: NC(=O)c1cccc(c1)-c1ccc(cc1)S(=O)(=O)Nc1ccc2CCCN(C(=O)C3CC3)c2c1. References: Ling Zhang, et al. OGG1 co-inhibition...
Anwendung: | OGG1 inhibitor |
CAS | 2210228-45-6 |
MW: | 475.56 D |
ab 42,00 €
Artikelnummer: TGM-TMPH-01774-100ug
Description: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. OGG1 Protein, Human, Recombinant (His) is expressed in E. coli expression...
Schlagworte: | N-glycosylase/DNA lyase, OGG1 |
MW: | 42.8 kD |
ab 198,00 €
Artikelnummer: CSB-EP016313HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-345aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MPARALLPRR MGHRTLASTP ALWASIPCPR SELRLDLVLP SGQSFRWREQ SPAHWSGVLA DQVWTLTQTE EQLHCTVYRG DKSQASRPTP DELEAVRKYF QLDVTLAQLY HHWGSVDSHF QEVAQKFQGV...
Schlagworte: | MMH, OGG1, AP lyase, EC=3.2.2.-, EC=4.2.99.18, N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 42.8 kD |
ab 219,00 €
Artikelnummer: CSB-EP016313HUa2.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-345aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MPARALLPRR MGHRTLASTP ALWASIPCPR SELRLDLVLP SGQSFRWREQ SPAHWSGVLA DQVWTLTQTE EQLHCTVYRG DKSQASRPTP DELEAVRKYF QLDVTLAQLY HHWGSVDSHF QEVAQKFQGV...
Schlagworte: | MMH, OGG1, AP lyase, EC=3.2.2.-, EC=4.2.99.18, N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 54.8 kD |
ab 219,00 €
Artikelnummer: CSB-YP016313HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-345aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MPARALLPRR MGHRTLASTP ALWASIPCPR SELRLDLVLP SGQSFRWREQ SPAHWSGVLA DQVWTLTQTE EQLHCTVYRG DKSQASRPTP DELEAVRKYF QLDVTLAQLY HHWGSVDSHF QEVAQKFQGV RLLRQDPIEC...
Schlagworte: | MMH, OGG1, AP lyase, EC=3.2.2.-, EC=4.2.99.18, N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or... |
Anwendung: | Activity not tested |
Exprimiert in: | Yeast |
Ursprungsart: | human |
MW: | 40.8 kD |
ab 292,00 €
Artikelnummer: ARG64260.100
Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. [The UniProt Consortium]
Schlagworte: | Anti-Ogg1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA glycosylase,... |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | rat |
822,00 €
Artikelnummer: G-HUFI01316.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: NSJ-R34250-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 8-oxoguanine DNA glycosylase Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine...
Schlagworte: | Anti-Ogg1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA glycosylase,... |
Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
Wirt: | Goat |
Spezies-Reaktivität: | mouse, rat |
790,00 €
Artikelnummer: NSJ-F49970-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Protein function: DNA repair enzyme that incises DNA...
Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 350,00 €
Artikelnummer: E-AB-60300.120
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants...
Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €