Zu "K03660" wurden 49 Artikel gefunden!
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TH10785
Artikelnummer: Cay43043-10
TH10785 is an 8-oxoguanine DNA glycosylase 1 (OGG1) activator. It increases OGG1-mediated excision of 8-oxoguanine (8-hydroxyguanine, Cay-89290) in duplex oligonucleotides when used at a concentration of 10 µM. TH10785 (10, 30, or 100 µM) inhibits oxidative damage in A549 cells induced by paraquat (Cay-38521). It...
| Schlagworte: | N-cyclohexyl-2-cyclopropyl-4-quinazolinamine |
| Anwendung: | OGG1 activator |
| CAS | 1002801-51-5 |
| MW: | 267.38 D |
ab 101,00 €
Anti-Ogg1, Internal
Artikelnummer: ARG64260.100
Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. [The UniProt Consortium]
| Schlagworte: | Anti-Ogg1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA glycosylase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | rat |
871,00 €
Human 8-oxoGuanine DNA Glycosylase / OGG1 ELISA Kit
Artikelnummer: G-HUFI01316.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-Ogg1
Artikelnummer: NSJ-R34250-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 8-oxoguanine DNA glycosylase Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine...
| Schlagworte: | Anti-Ogg1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA glycosylase,... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse, rat |
836,00 €
Anti-OGG1
Artikelnummer: NSJ-F49970-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. OGG1 is the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Protein function: DNA repair enzyme that incises DNA...
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-OGG1
Artikelnummer: E-AB-60300.120
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants...
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €
Anti-Ogg1
Artikelnummer: ARG40512.100
Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. [The UniProt Consortium]
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
616,00 €
Anti-Ogg1
Artikelnummer: ARG40520.100
Protein function: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion. [The UniProt Consortium]
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
707,00 €
OGG1-IN-O8
Artikelnummer: Cay29769-1
OGG1-IN-O8 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1, IC50 = 0.35 µM). It is selective for OGG1 over Nei-like DNA glycosylase 1 (NEIL1), endonuclease III homolog 1 (NTH1), and formamidopyrimidine DNA glycosylase (Fpg) at 50 µM.Formal Name: 3,4-dichloro-benzo[b]thiophene-2-carboxylic acid, hydrazide....
| Schlagworte: | 3,4-dichloro-benzo[b]thiophene-2-carboxylic acid, hydrazide |
| Anwendung: | OGG1 inhibitor |
| CAS | 350997-39-6 |
| MW: | 261.1 D |
ab 54,00 €
Anti-OGG1, clone CPTC-OGG1-1
Artikelnummer: NSJ-V7991-100UG
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. 8-oxoguanine (8-oxoG), an oxidized form of guanine, is produced by reactive oxygen species in both DNA and nucleotide pools during normal aging. Accumulation of 8-oxoG increases the occurrence of A:T to C:G or G:C to T:A transversionmutations, because...
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-OGG1, clone CPTC-OGG1-1
Artikelnummer: NSJ-V7991SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. 8-oxoguanine (8-oxoG), an oxidized form of guanine, is produced by reactive oxygen species in both DNA and nucleotide pools during normal aging. Accumulation of 8-oxoG increases the occurrence of A:T to C:G or G:C to T:A transversionmutations, because 8-oxoG forms a...
| Schlagworte: | Anti-MMH, Anti-OGG1, Anti-AP lyase, EC=3.2.2.-, EC=4.2.99.18, Anti-N-glycosylase/DNA lyase, Anti-8-oxoguanine DNA... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
SU 0268
Artikelnummer: Cay36064-1
SU 0268 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1, IC50 = 0.059 µM). It is selective for OGG1 over the DNA repair enzymes MTH1, dUTPase, NUDT16, ABH2, ABH3, and SMUG1 at 20 µM. SU 0268 (0.5 µM) inhibits OGG1 and increases the number of 8-oxoguanine DNA lesions in HeLa cell lysates.Formal Name:...
| Schlagworte: | 4'-[[[1-(cyclopropylcarbonyl)-1,2,3,4-tetrahydro-7-quinolinyl]amino]sulfonyl]-[1,1'-biphenyl]-3-carboxamide |
| Anwendung: | OGG1 inhibitor |
| CAS | 2210228-45-6 |
| MW: | 475.6 D |
ab 45,00 €