Nudifloramide

Nudifloramide is an active metabolite of the cofactor, biological intermediate, and NAD+ biosynthetic precursor nicotinamide (Cay-11127). It is formed from nicotinamide via a 1-methylnicotinamide (Cay-16604) intermediate by aldehyde oxidase (AOX). Nudifloramide is an inhibitor of poly(ADP-ribose) polymerase (PARP, IC50 = 8 µM). Plasma levels of nudifloramide are increased in patients with chronic renal failure.Formal Name: 1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxamide. CAS Number: 701-44-0. Synonyms: N-methyl-2-Pyridone-5-Carboxamide, Met2PY, 2-Py. Molecular Formula: C7H8N2O2. Formula Weight: 152.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 3 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 257, 301 nm. SMILES: O=C(N)C(C=C1)=CN(C)C1=O. InChi Code: InChI=1S/C7H8N2O2/c1-9-4-5(7(8)11)2-3-6(9)10/h2-4H,1H3,(H2,8,11). InChi Key: JLQSXXWTCJPCBC-UHFFFAOYSA-N.