NM107

Description: NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity and acts as a nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, demonstrating an EC50 of 1.85 µM in wild-type replicon cells. Target: HCV Protease. Smiles: C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc(N)nc1=O. References: Goris N , De Palma A , Toussaint, JeanFrançois, et al. 2'-C-Methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virus[J]. Antiviral Research, 2007, 73(3):161-168.