Nitidine chloride

Description: 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and identifies efficacy in vivo in a mouse model of HCC. Target: p38 MAPK, ERK, FAK, Apoptosis, Parasite, Topoisomerase, NF-kappaB, STAT. Smiles: [Cl-].COc1cc2c[n+](C)c3c(ccc4cc5OCOc5cc34)c2cc1OC. References: Wang Z , Jiang W , Zhang Z , et al. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells[J]. Journal of ethnopharmacology, 2012, 144(1).