NFAT:AP-1 inhibitor-10

Description: NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosporin A-sensitive cytokine genes important for the effector immune response. Target: Others. Smiles: S(CC(NC1=CC(NC(C)=O)=CC=C1)=O)C=2C=CC(C=3NC=4C(N3)=CC=CC4)=CN2