Naltrindole (hydrochloride)

Naltrindole is a potent antagonist of the human delta-opioid receptor (Ki = 0.02-0.3 nM), with much lower affinities for kappa- and µ-opioid receptors (Kis = 10-66 and 6-64 nM, respectively). Naltrindole is commonly used to investigate the role of the delta-opioid receptor in signaling responses to test compounds.Formal Name: (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, monohydrochloride. CAS Number: 111469-81-9. Molecular Formula: C26H26N2O3 . HCl. Formula Weight: 451.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: 10 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 210, 284 nm. SMILES: O[C@]12[C@]3(CCN(CC4CC4)[C@@H]2C5)[C@](OC6=C3C5=CC=C6O)([H])C(NC7=C8C=CC=C7)=C8C1.Cl. InChi Code: InChI=1S/C26H26N2O3.ClH/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14,/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2,1H/t20-,24+,25+,26-,/m1./s1. InChi Key: KNJKRQXCFJCQHC-IDRHMUJXSA-N.