N-desmethyl Levofloxacin (hydrochloride)

N-desmethyl Levofloxacin is an active metabolite of the fluoroquinolone antibiotic levofloxacin (Cay-20382). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 4, 1, 1, 0.012, >4, and 0.25 µg/ml, respectively).Formal Name: (3S)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, hydrochloride. Synonyms: Desmethyl Levofloxacin. Molecular Formula: C17H18FN3O4 . XHCl. Formula Weight: 383.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 223, 294, 326 nm. SMILES: FC1=C(N2CCNCC2)C(OC[C@H](C)N3C=C(C(O)=O)C4=O)=C3C4=C1.Cl. InChi Code: InChI=1S/C17H18FN3O4.ClH/c1-9-8-25-16-13-10(15(22)11(17(23)24)7-21(9)13)6-12(18)14(16)20-4-2-19-3-5-20,/h6-7,9,19H,2-5,8H2,1H3,(H,23,24),1H/t9-,/m0./s1. InChi Key: IOFZKWNXVPUJLW-FVGYRXGTSA-N.