MK-2118

MK-2118 is an agonist of stimulator of interferon genes (STING). It induces STING signaling in a reporter assay using membranes expressing human STING (EC50 = 2. µM). MK-2118 (30 µM) induces IFN-beta secretion in THP-1 monocytes. InChI: InChI=1S/C15H16O5S/c1-8(15(17)18)4-10(16)14-6-9-5-11(19-2)12(20-3)7-13(9)21-14/h5-8H,4H2,1-3H3,(H,17,18)/t8-/m0/s1 InChIKey: WBHPMBQELUEIIV-QMMMGPOBSA-N SMILES: OC([C@@H](C)CC(C1=CC2=CC(OC)=C(C=C2S1)OC)=O)=O