MIK665

MIK665 is an inhibitor of myeloid cell leukemia-1 (Mcl-1, Ki = 1.2 nM).Formal Name: alphaR-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-phenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-benzenepropanoic acid. CAS Number: 1799631-75-6. Synonyms: S64315. Molecular Formula: C47H44ClFN6O6S. Formula Weight: 875.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: O=C(C(CC1=C(OCC2=NC(C3=C(OC)C=CC=C3)=NC=C2)C=CC=C1)OC4=C5C(C6=C(C)C(Cl)=C(OCCN7CCN(CC7)C)C=C6)=C(C8=CC=C(C=C8)F)SC5=NC=N4)O. InChi Code: InChI=1S/C47H44ClFN6O6S/c1-29-34(16-17-38(42(29)48)59-25-24-55-22-20-54(2)21-23-55)40-41-45(51-28-52-46(41)62-43(40)30-12-14-32(49)15-13-30)61-39(47(56)57)26-31-8-4-6-10-36(31)60-27-33-18-19-50-44(53-33)35-9-5-7-11-37(35)58-3/h4-19,28,39H,20-27H2,1-3H3,(H,56,57). InChi Key: PKYIMGFMRFVOMB-UHFFFAOYSA-N.