Zu "K02539" wurden 123 Artikel gefunden!
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Anti-Mcl-1 (Myeloid Cell Leukemia-1)
Artikelnummer: 600-401-394
Protein function: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. [The UniProt Consortium]
| Schlagworte: | Anti-Mcl1, Anti-Bcl-2-related protein EAT/mcl1, Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
733,00 €
NEU
Mouse MCL1 (Myeloid Cell Leukemia Sequence 1, Bcl2...
Artikelnummer: ELK-ELK7001MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse MCL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse MCL1. Next,...
| Schlagworte: | Mcl1, Bcl-2-related protein EAT/mcl1, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Anti-MCL1 (recombinant antibody)
Artikelnummer: ABS-RC-6698.100
Formulation: Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide,pH 7.3. Identity-Mouse (%): . Homologies: . IHC Verification: -. WB Verification: succeed. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification:...
| Schlagworte: | Anti-MCL1, Anti-mcl1/EAT, Anti-Bcl-2-like protein 3, Anti-Bcl-2-related protein EAT/mcl1, Anti-Induced myeloid leukemia... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat,human |
ab 206,00 €
PROTAC Mcl Degrader-1
Artikelnummer: Cay45150-10
A PROTAC that drives Mcl-1 degradation, induces degradation of Mcl-1 in HeLa cells (DC50 = 0.76 µM), induces selective degradation of Mcl-1 over Bcl-2, Bcl-xL, MDM2, and tubulin in HeLa cells at 10 µM, inhibits growth of H23 cells. SMILES:...
| Schlagworte: | Proteolysis-targeting Chimera Mcl Degrader-1,... |
| Anwendung: | Mcl-1 degradation driving PROTAC |
| CAS | 2163793-38-0 |
| MW: | 909.85 D |
ab 91,00 €
Anti-MCL, Rat, mAb WEN42
Artikelnummer: HYC-HM3042-100UG
For immunohistochemistry, flow cytometry, immunoprecipitation and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
| Schlagworte: | Anti-Mcl1, Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| Anwendung: | FC, IHC-F, FA, IP, WB |
| Spezies-Reaktivität: | rat |
ab 139,00 €
MCL1, His-Tag
Artikelnummer: BPS-40742
Human MCL1, also known as Induced myeloid leukemia cell differentiation protein and BCL2L3, GenBank Accession No. NM_021960, a.a. 2-327, with N-terminal His-tag, expressed in an E. coli expression system.
| Schlagworte: | MCL1, BCL2L3, Bcl2-L-3, mcl1/EAT, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Induced myeloid leukemia cell... |
| Anwendung: | Apoptosis studies, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 36 kD |
528,00 €
MCL-1 Peptide Ligand
Artikelnummer: BPS-79507
MCL-1 Peptide Ligand is useful as a substrate for screening services and optimized for use with the following TR-FRET assay kits: * MCL-1 TR-FRET Assay kit (BPS-79506) * MCL-1 TR-FRET Assay kit (Mouse) (BPS-79928)
| Anwendung: | Substrate, screening, TR-FRET |
| MW: | 3162 D |
446,00 €
MCL-1 TR-FRET Assay Kit
Artikelnummer: BPS-79506
The MCL-1 TR-FRET Assay Kit is designed to measure the inhibition of MCL-1 binding to its ligand in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and...
| Schlagworte: | mcl1, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.365,00 €
MCL-1 TR-FRET Assay Kit (Mouse)
Artikelnummer: BPS-79928
The Mouse MCL-1 TR-FRET Assay Kit is designed to measure the inhibition of mouse MCL-1 binding to its ligand in a homogeneous 384 reaction format. This TR-FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is...
| Schlagworte: | MCL1 assay kit, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | mouse |
1.365,00 €
MCL-1 TR-FRET Assay Kit (Rat)
Artikelnummer: BPS-78804
The Induced myeloid leukemia cell differentiation protein (MCL-1) TR-FRET Assay Kit (Rat) is designed to measure the inhibition of rat MCL-1 binding to its ligand in a homogeneous 384-well format. This TR-FRET based assay requires no time-consuming washing steps, making it especially suitable for high throughput...
| Schlagworte: | Mcl1, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | rat |
1.365,00 €
Anti-Mcl-1
Artikelnummer: 600-401-394S
This affinity-purified antibody was prepared from monospecific antiserum by immunoaffinity chromatography using synthetic peptide coupled to agarose beads followed by cross adsorption to remove any unwanted reactivity. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. No...
| Schlagworte: | Anti-Mcl1, Anti-Bcl-2-related protein EAT/mcl1, Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
180,00 €
S63845
Artikelnummer: Cay21131-5
S63845 is an inhibitor of myeloid cell leukemia 1 (Mcl-1, Ki = 0.19 nM), a pro-survival protein that is overexpressed in many cancers. It induces cell death in multiple myeloma, leukemia, and lymphoma cell lines (IC50s = via mitochondrial apoptosis. S63845 acts synergistically with trametinib (Cay-16292), lapatinib...
| Schlagworte: | alpha(R)-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimi... |
| Anwendung: | Mcl-1 inhibitor |
| CAS | 1799633-27-4 |
| MW: | 829.3 D |
ab 133,00 €