Menin-MLL Inhibitor 20

Menin-MLL inhibitor 20 is a synthetic intermediate in the production of the irreversible inhibitor of the protein-protein interaction between MLL and menin, BMF-219, which induces cytotoxicity in cancer cells in vitro.Formal Name: N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-carbamic acid, 1,1-dimethylethyl ester. CAS Number: 2448173-47-3. Molecular Formula: C33H40N8O4. Formula Weight: 612.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Sparingly Soluble: 1-10 mg/ml. SMILES: O=C(N[C@@H]1CCCN(CC2=CC=NC(C(NC3=CC=C(C4=CC5=C(N6CCOCC6)N=CN=C5N4)C=C3)=O)=C2)C1)OC(C)(C)C. InChi Code: InChI=1S/C33H40N8O4/c1-33(2,3)45-32(43)38-25-5-4-12-40(20-25)19-22-10-11-34-28(17-22)31(42)37-24-8-6-23(7-9-24)27-18-26-29(39-27)35-21-36-30(26)41-13-15-44-16-14-41/h6-11,17-18,21,25H,4-5,12-16,19-20H2,1-3H3,(H,37,42)(H,38,43)(H,35,36,39)/t25-/m1/s1. InChi Key: MPFHTFMFYAODPE-RUZDIDTESA-N.